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Identification of CDK4/6 Inhibitors as Small Molecule NLRP3 Inflammasome Activators that Facilitate IL-1β Secretion and T Cell Adjuvanticity

https://doi.org/10.1021/acs.jmedchem.4c00516

Weiss, Adam M; Lopez, Marcos A; Rosenberger, Matthew G; Kim, Jeremiah Y; Shen, Jingjing; Chen, Qing; Ung, Trevor; Ibeh, Udoka M; Knight, Hannah Riley; Rutledge, Nakisha S; et al (September 2024, Journal of Medicinal Chemistry)

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Understanding How Cationic Polymers’ Properties Inform Toxic or Immunogenic Responses via Parametric Analysis

https://doi.org/10.1021/acs.macromol.3c01223

Weiss, Adam M.; Lopez, Marcos A.; Rawe, Benjamin W.; Manna, Saikat; Chen, Qing; Mulder, Elizabeth J.; Rowan, Stuart J.; Esser-Kahn, Aaron P. (September 2023, Macromolecules)

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